Cathryn Nagler Lab

Microbial ambassadors against food allergies

Early disruptions in the composition of the gut microbiome can directly influence digestive and immune function in ways that put children at greater risk.


Dr. Nagler’s presentation on campus, April 2019

National Geographic: The Microbiome Menagerie

Trillions of microbes call our body home. Now we’re learning they are crucial for our health

The Nagler Lab Team

[left to right] Valeria Ruiz, Dr. Shijie Cao, Matthew Sabados, Andrew Thompson, Sung Min Choi Hong, Evelyn Campbell, Jack Arnold, Dr. Mohamed Bashir, Dante Moreno, Matthew Bauer, Lauren Hesser, Anjali Mirmira, Nidhi Talasani, Dr. Andrea Kemter, and Dr. Cathryn Nagler

The End of an Epidemic

The number of people with food allergies has exploded in recent years. A dream team of Chicago researchers and scientists may have figured out why, and now they’re developing therapies that could lead to…

The Nagler Laboratory

How do immune cells in the intestinal mucosa distinguish innocuous dietary antigens and trillions of commensal bacteria from pathogenic microbes and mount an appropriate response to each?

Our laboratory is pursuing several different, but complementary, lines of research aimed at examining the mechanisms regulating non-responsiveness to these stimuli in healthy individuals and its abrogation in food allergy. Our murine disease models will provide the pre-clinical basis for future translational studies aimed ultimately at the development of novel immunotherapeutic modalities.