Publications

2017

  • Kim YG, Sakamoto K, Seo SU, Pickard JM, Gillilland MG 3rd, Pudlo NA, Hoostal M, Li X, Wang TD, Feehley T, Stefka AT, Schmidt TM, Martens EC, Fukuda S, Inohara N, Nagler CR, Núñez G. Neonatal acquisition of Clostridia species protects against colonization by bacterial pathogens. Science. 2017 Apr 21;356(6335):315-319. Full paper here.
  • Plunkett CH, Nagler CR. The Influence of the Microbiome on Allergic Sensitization to Food. J Immunol. 2017 Jan 15;198(2):581-589. Full paper here.

2016

  • Aitoro R, Simeoli R, Amoroso A, Paparo L, Nocerino R, Pirozzi C, di Costanzo M, Meli R, De Caro C, Picariello G, Mamone G, Calignano A, Nagler CR, Berni Canani R. Extensively hydrolyzed casein formula alone or with L. rhamnosus GG reduces β-lactoglobulin sensitization in mice. Pediatr Allergy Immunol. 2016 Dec 19. 2016: 00. Full paper here.
  • Nutsch K, Chai JN, Ai TL, Russler-Germain E, Feehley T, Nagler CR, Hsieh CS. Rapid and Efficient Generation of Regulatory T Cells to Commensal Antigens in the Periphery. Cell Rep. 2016 Sep 27;17(1):206-20. Full paper here.
  • Lei, Y.K., Chen, L., Wang, Y., Stefka, A.T., Nair, L., Molinero, L., Theriault, B., Aquino-Michaels, K., Sivan, A., Nagler, C.R., Gajewski, T.F., Chong, A.S., Bartman, C. and Alegre, M.L. The composition of the microbiota modulates skin allograft rejection. J Clin Invest. 2016. Jul 1;126(7):2736-44. Full paper here.
  • Feehley T, Belda-Ferre P, Nagler CR. What's LPS Got to Do with It? A Role for Gut LPS Variants in Driving Autoimmune and Allergic Disease. Cell Host Microbe. 2016 May 11;19(5):572-4. Full paper here.
  • Wesemann DR, Nagler CR. The Microbiome, Timing, and Barrier Function in the Context of Allergic Disease. Immunity. 2016 Apr 19;44(4):728-38. Full paper here.
  • Berni Canani R, Sangwan N, Stefka AT, Nocerino R, Paparo L, Aitoro R, Calignano A, Khan AA, Gilbert JA, Nagler CR. Lactobacillus rhamnosus GG-supplemented formula expands butyrate-producing bacterial strains in food allergic infants. ISME J. 2016 Mar;10(3):742-50. Full paper here.

​2015

  • Yano JM, Yu K, Donaldson GP, Shastri GG, Ann P, Ma L, Nagler CR, Ismagilov RF, Mazmanian SK, Hsiao EY. Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell. 2015 Apr 9;161(2):264-76.Abstract here.
  • Berni Canani R, Gilbert JA, Nagler CR. The role of the commensal microbiota in the regulation of tolerance to dietary allergens. Curr Opin Allergy Clin Immunol. 2015 Jun;15(3):243-9. Abstract here.
  • Lax S, Nagler CR, Gilbert JA. Our interface with the built environment: immunity and the indoor microbiota. Trends Immunol. 2015 Mar;36(3):121-3. Abstract here.

2014

  • Feehley T, Nagler CR. Cellular and molecular pathways through which commensal bacteria modulate sensitization to dietary antigens. Curr Opin Immunol. 2014 Dec;31:79-86 Abstract here.
  • Cao, S., Feehley, T., and Nagler, C.R. The role of commensal bacteria in the regulation of sensitization to food allergens. FEBS Lett. 2014 Nov 17;588(22):4258-66. Article here.
  • Feehley T, Nagler CR. Health: The weighty costs of non-caloric sweeteners. Nature. 2014 Oct 9;514(7521):176-7. Article here.
  • Stefka, A.T, Feehley, T., Tripathi, P., Qiu, J.,McCoy, K., Mazmanian, S., Seo, G-Y., Cao, S., Theriault, B, Antonopoulos, D., Zhou, L., Chang, E.B., Fu, Y-X., and C.R. Nagler. Commensal bacteria protect against food allergen sensitization.Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13145-50. Abstract here.

2012

  • Feehley, T., Stefka, A.T., Cao, S. and C.R. Nagler. Microbial regulation of allergic responses to food. Semin. Immunopathol. 2012, 34: 671-688. Article available hereFull Issue:C.R.Nagler, Ed.
  • Upadhyay, V., Poroyko, V., Kim, T.J., Devkota, S., Fu, S., Liu, D., , Deng, L., Nagler, C., Chang, E.B, Tang,H. and Fu, Y-F. Lymphotoxin regulates commensal responses to enable diet-induced obesity. Nat. Immunol. 2012, 13: 947-953.

2011

  • Wang, S. Villablanca, E.J., De Calisto, J., Gomes, D.C.O., Nguyen, D.D., Mizoguchi, E., Kagan, J.C., Reinecker, H.-C., Hacohen, N., Nagler, C., Xavier, R.J., Rossi-Bergmann, B., Chen, Y-B., Blomhoff, R., Snapper, S.B. and Mora, J.R. MyD88-dependent TLR1/2 signals educate dendritic cells with gut- specific imprinting properties. J. Immunol. 2011, 187: 141-150.
  • Wang, Y., Devkota, S., Musch, M.W., Jabri, B., Nagler, C., Antonopoulos, D.A., Chervonsky, A and E.B. Chang. Regional mucosa- associated microbiota determine physiological expression of TLR2 and TLR4 in murine colon. PLoS ONE 2010, 5: e13607.
  • McBee M.E., Zeng Y, Parry N, Nagler C.R., Tannenbaum S.R. and D.B. Schauer. Multivariate modeling identifies neutrophil- and Th17-related factors as differential serum biomarkers of chronic murine colitis. PLoS ONE 2010, 5: e13277.
  • Matharu, K.S, Mizoguchi, E., Alonso, C., Nguyen D., Mingle, B., Iweala, O.I., McBee, M. Stefka, AT, Prioult, G, Haigis, K.M., Bhan, A.K., Snapper, S.B., Murakami, H, Schauer D.B. Reinecker,H.C Mizoguchi, A. and C. R. Nagler. Toll-like receptor 4-mediated regulation of spontaneous Helicobacter-dependent colitis in IL-10 deficient mice. Gastroenterology 2009, 137:1380–1390.
  • Iweala, O.I., Smith, D.S., Matharu, K.S., Sada-Ovalle, I..,DeKruyff, R.H., Umetsu, D.T., Behar, S.M and C. R. Nagler. Vaccine induced antibody isotypes are skewed by impaired CD4 T cell and invariant NKT cell effector responses in MyD88 deficient mice. J. Immunol., 2009, 183: 2252-2260.
  • Bashir, M.E.H., Louie, S., Shi, H.N. and C. Nagler-Anderson. TLR-4 signaling by intestinal microbes influences susceptibility to food allergy. J.Immunol., 2004, 172, 6978-6987.
  • Bashir, M.E.H., Andersen, P., Fuss, I.J., Shi, H.N. and C. Nagler-Anderson. An enteric helminth infection protects against an allergic response to dietary antigen. J. Immunol. 2002, 169:3284-3292.
  • Shi, H.N., Liu, H.Y. and C. Nagler-Anderson. Enteric infection acts as an adjuvant for the response to a model food antigen, J. Immunol., 2000, 165: 6174-6182.
  • Fox, J.G., Beck, P., Dangler, C.A., Whary, M.T., Wang, T.C., Shi, H.N. and C. Nagler-Anderson. Concurrent enteric helminth infection modulates inflammation, gastric immune responses, and reduces Helicobacter-induced gastric atrophy. Nature Medicine 2000; 6: 536-542.
  • Shi, H.N., Ingui, C. J., Dodge, I. and C. Nagler-Anderson. A helminth induced mucosal Th2 response alters non-responsiveness to oral administration of soluble antigen. J. Immunol. 1998;160:2449-2455.
  • Nagler-Anderson, C., Bober, L.A., Robinson, M.E., Siskind, G.W. and Thorbecke, G.J. Suppression of type II collagen induced arthritis by intragastric administration of soluble type II collagen. Proc. Natl. Acad. Sci. 1986; 83: 7443-7446.